• Home
  • Browse
    • Current Issue
    • By Issue
    • By Author
    • By Subject
    • Author Index
    • Keyword Index
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Peer Review Process
  • Guide for Authors
  • Submit Manuscript
  • Reviewers
  • Contact Us
 
  • Login
  • Register
Home Articles List Article Information
  • Save Records
  • |
  • Printable Version
  • |
  • Recommend
  • |
  • How to cite Export to
    RIS EndNote BibTeX APA MLA Harvard Vancouver
  • |
  • Share Share
    CiteULike Mendeley Facebook Google LinkedIn Twitter
The Egyptian Journal of Community Medicine
arrow Articles in Press
arrow Current Issue
Journal Archive
Volume Volume 38 (2020)
Issue Issue 4
Issue Issue 3
Issue Issue 2
Issue Issue 1
Volume Volume 37 (2019)
Volume Volume 36 (2018)
Volume Volume 35 (2017)
Volume Volume 34 (2016)
Volume Volume 33 (2015)
(2020). To What Extent Assisted Reproductive Technology Is Risky?. The Egyptian Journal of Community Medicine, 38(4), 24-34. doi: 10.21608/ejcm.2020.119412
. "To What Extent Assisted Reproductive Technology Is Risky?". The Egyptian Journal of Community Medicine, 38, 4, 2020, 24-34. doi: 10.21608/ejcm.2020.119412
(2020). 'To What Extent Assisted Reproductive Technology Is Risky?', The Egyptian Journal of Community Medicine, 38(4), pp. 24-34. doi: 10.21608/ejcm.2020.119412
To What Extent Assisted Reproductive Technology Is Risky?. The Egyptian Journal of Community Medicine, 2020; 38(4): 24-34. doi: 10.21608/ejcm.2020.119412

To What Extent Assisted Reproductive Technology Is Risky?

Article 4, Volume 38, Issue 4, Autumn 2020, Page 24-34  XML PDF (664.11 K)
Document Type: Original Article
DOI: 10.21608/ejcm.2020.119412
Abstract
Background: The number of infants born after assisted reproductive technology (ART) is increasing worldwide. Concerns are rising regarding its safety with inconsistent results. Objective: to explore maternal and child health outcomes following ART. Method: The current case-control study was conducted in Alexandria from January to December 2018. Target population was all children that attended El-Shatby Pediatric University Hospital during the period of study. Interviewing questionnaire, clinical examination, and radiological investigation were the tools of data collection. Results: The present study involved 113 singleton children born after ART and a similar number of naturally conceived controls. It showed that among ART group; subfertility was primary in 90.3% and mostly due to male factor (64.6%). The study revealed that ART mothers were more likely to have hypertension in pregnancy (OR=4.8), preeclampsia (OR= 4.3), gestational diabetes (OR=3.4) placenta previa (OR=2.8), premature rupture of membrane (OR=2.7) and Caesarean section (OR= 2.3) versus naturally conceived (NC) women. ART children were more prone to low birth weight (OR=3.2), admission to neonatal intensive care unit (OR=4.9) or hospital (OR=2.4) with longer stay (p=0.001) versus naturally conceived children. Odds of Autism spectrum disorders (OR= 5.4) and global developmental delay (OR= 4.4) were higher among children born after ART than among controls. Major and multiple congenital anomalies were more likely to be observed among ART (OR=4.5 and OR= 2.1 respectively) versus NC children. Anomalies of the cardio vascular and central nervous systems (4.4% each) were the most frequent. Adversely affected ART children (100%) were well accepted within their families and all primary subfertile mothers (90.3%) were welling to have more. Conclusion and recommendations: Our study confirmed an increased risk of adverse maternal and child outcome after ART. Pre-implantation genetic screening, careful neonatal examination, long term follow up of ART children, and prospective studies to assess early and delayed ART outcomes and their determinants are recommended.
Keywords
Assisted reproductive Technology; safety; newborn
Statistics
Article View: 44
PDF Download: 52
Home | Glossary | News | Aims and Scope | Sitemap
Top Top

Journal Management System. Designed by NotionWave.